Effects of Nano Zinc Oxide on the Hind Limb Bud of NMRI mouse embryos

Nanomaterials are particles with 10 to100 nanometer size. They can easily be transportedthrough the skin, lung alveoli, and placenta. Materials in nano scales show different propertiescompared with the same materials in macro or larger scale. It is found that zinc element is anessential metal for normal physiological functions. However increase or decrease of this elementduring pregnancy, for example with using cosmetics and deodorants, can be teratogen and causeseveral fetal abnormalities. Given this fact, this study was conducted to investigate the effects ofnano zinc oxide on the developmental stages of hind limb budsin NMRI mice embryos